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Chronic Obstructive Pulmonary Disease (COPD)


The liver may be the most important single organ that maintains the body. It is the storehouse glycogen, enzymes and proteins, copper, iron, and vitamin A.  The liver also helps regulate blood volume. It also manufactures blood-clotting factors and blood proteins, and affects the metabolism of proteins, carbohydrates, and fats. The liver is also the primary detoxification organ to remove the poisonous effects of foreign substances in the blood such as bacterial toxins. Very few pharmaceuticals available in equine practice treat the liver specifically. The liver metabolizes many drugs, so if it is functioning poorly, these drugs may be too toxic to use safely. Natural compounds improve the cytochrome P450 detoxification pathways as well as act as anti-inflammatories.





In addition, careful and continuous monitoring of all food sources, including both pastures and feed, along with the barn, stable and arena environments will help the horse owner identify and eliminate the potential toxins or parasites that potentially cause liver disease.


Once hepatitis has been diagnosed, recommended treatment should start with a low-protein diet, intravenous glucose, vitamins, IV amino acids, mineral oil, oral antibiotics, steroids and sedatives (if needed).


Antibiotics are used to both curb and control any secondary infections -- bacterial or otherwise -- that occur as a result of the hepatitis. The antibiotics will also help reduce the effects of any ingested toxins that may have had on the body.

Any glucose will assist in maintaining the afflicted horse's vitamin and glucose levels in its bloodstream while the animal is being detoxified of any poisonous effects of foreign substances in the blood. Mineral oil by mouth will further reduce the uptake of toxins from the gut.


Integrative Medicine


» Vitamin B Supplements: assists in healing damaged liver cells.


» Milk Thistle Extract:  helps the liver detoxify during drug therapy. Also known as St. Mary’s Thistle, Holy Thistle and Blessed Thistle is most commonly recommended for horses with liver or kidney damage as it protects the liver from circulating toxins from chemicals, and bad reactions to surgical procedures and drugs. The active compound, Silymarin, has been clinically proved to stimulate the regenerative (or regrowth) properties of the liver. Thistle Extract has been deemed safe for long-term, high dosages, in severely debilitated or aged horses. 



(Reference: Veterinarians’ Desk Reference)

(Live Link)


Species affected: Equines.


Background: An inflammation of the liver that may or may not include an infectious process as well.


Symptoms: Jaundice, pain, digestive upset, fever, PU/PD, incidental findings of elevated liver enzymes, Lyme disease.


Diagnostics: Blood tests, a thorough history and physical examination. Possible hair analysis for toxins, though many companies use unreliable hair data to sell products.


Special Notes: Horses exposed to toxins such as heavy metals or noxious plants may become ill. One significant source of hepatic toxins is treated wood, common in many horse facilities. A diet of fresh, healthy food and removal of any toxins in the environment is critical to these horses.


Principles for Supplementation: Support the hepatic processes of detoxification, while not over-stimulating any one part of its pathways.









1 scoop bid

Down-regulates the pro-inflammatory substances, tumor necrosis factor, alpha (TNF-α) and nuclear factor-kappaB (NF-κB), supports normal liver function.


6-12 capsules sid

Is a cofactor for dozens of enzymes involved in detoxification, provides hepatic support.

Long Dan Xie Gan Tang  (Gentiana Combination)14

4 tsp bid

Clears Damp Heat, inflammation and itching of the skin, temperamental.

Hilton Hepaphyt2

2-4 scoops bid

Supports liver detoxification pathways.

Hilton Hepaphyt Gold2

2-4 scoops bid

Supports liver detoxification pathways.


6-10 mL sid

Adaptogenic herbs, support the immune system, adrenals, reduces stress, helps horses adapt to stress.


6-10 capsules sid

Support liver detoxification pathways, hepatoprotective effects.


To help you quickly find the right Integrative Medicine formulas and manufacturers to help treat your dogs, cats and horses, please refer to the Veterinarians’ Desk Reference
(Click Here)


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